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@mackelab

mackelab

Machine Learning in Science at University of Tübingen, Germany

Machine Learning in Science

Our goal is to accelerate scientific discovery using machine learning and artificial intelligence: We develop computational methods that help scientists interpret empirical data and use them to gain scientific insights.

We closely collaborate with experimental researchers from various disciplines. We are particularly interested in applications in the neurosciences: We build data-driven mechanistic models of neuronal functions in order to understand how neuronal networks in the brain process sensory information and control intelligent behaviour.

We are part of the Excellence Cluster Machine Learning Tübingen and the Tübingen AI Center. You can find out more about us on our lab website.

In addition to the repositories in this organization, (former) lab members have also developed the following toolboxes:

  • sbi, a toolbox for simulation-based inference,
  • DECODE, a deep learning tool for single molecule localization microscopy,
  • sbibm, a benchmark for simulation-based inference,
  • flyvis, a connectome constrained deep mechanistic network (DMN) model,
  • Jaxley, a differentiable simulator for biophysical neuron models.

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  1. mnle-for-ddms mnle-for-ddms Public

    Research code for Mixed Neural Likelihood Estimation (MNLE, Boelts et al. 2022)

    Jupyter Notebook 18 4

  2. phase-limit-cycle-RNNs phase-limit-cycle-RNNs Public

    Code for "Trained recurrent neural networks develop phase-locked limit cycles in a working memory task" - Matthijs Pals (@matthijspals) , Jakob Macke and Omri Barak.

    Python 7 3

  3. neural_timeseries_diffusion neural_timeseries_diffusion Public

    This repository contains research code for the paper "Generating realistic neurophysiological time series with denoising diffusion probabilistic models". @jsvetter

    Python 93 16

  4. sbi-ice sbi-ice Public

    Simulation-Based Inference of Surface Accumulation and Basal Melt Rates of an Antarctic Ice Shelf from Isochronal Layers

    Python 4

  5. STG_energy STG_energy Public

    Repo for STG energy paper. Michael (@michaeldeistler) and Pedro (@ppjgoncalves).

    Jupyter Notebook 1 1

  6. labproject labproject Public

    Labproject about comparing distributions metrics by @mackelab

    Python 4 1

Repositories

Showing 10 of 95 repositories
  • ModelSMC Public
    mackelab/ModelSMC's past year of commit activity
    Python 2 MIT 0 1 0 Updated Jul 30, 2026
  • tsnpe_neurips Public

    Code to reproduce results from `Truncated proposals for scalable and hassle-free simulation-based inference`

    mackelab/tsnpe_neurips's past year of commit activity
    Jupyter Notebook 4 AGPL-3.0 3 0 1 Updated Jul 25, 2026
  • tsnpe_neurips_data Public

    Results data (~3.1 GB, .pkl inference results) for mackelab/tsnpe_neurips — consumed as a submodule at l5pc/results/ to keep code clones free of Git LFS bandwidth.

    mackelab/tsnpe_neurips_data's past year of commit activity
    0 0 0 0 Updated Jul 25, 2026
  • epiphyte Public

    Python toolkit for working with high-dimensional neural data recorded during naturalistic, continuous stimuli

    mackelab/epiphyte's past year of commit activity
    Python 9 GPL-3.0 1 0 0 Updated Jun 12, 2026
  • PRIME Public
    mackelab/PRIME's past year of commit activity
    Jupyter Notebook 2 1 0 0 Updated Jun 3, 2026
  • velocity-hypothesis-test Public

    velotest: a hypothesis test for velocity visualisations by Sebastian @Baschdl

    mackelab/velocity-hypothesis-test's past year of commit activity
    Jupyter Notebook 0 MIT 0 2 0 Updated May 13, 2026
  • fnope Public

    Code for "FNOPE: Simulation-based inference on function spaces with Fourier Neural Operators"

    mackelab/fnope's past year of commit activity
    Python 1 MIT 0 0 1 Updated Apr 28, 2026
  • npe-pfn Public

    Minimal repository for the preprint "Effortless, Simulation-Efficient Bayesian Inference using Tabular Foundation Models"

    mackelab/npe-pfn's past year of commit activity
    Python 6 5 0 0 Updated Mar 20, 2026
  • prism Public
    mackelab/prism's past year of commit activity
    0 0 0 0 Updated Feb 25, 2026
  • LDNS Public
    mackelab/LDNS's past year of commit activity
    Jupyter Notebook 26 MIT 4 0 0 Updated Jan 30, 2026

People

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